Sentence examples for deleterious cells from inspiring English sources

As accelerated cell migration by chemopreventive agents has been reported to be beneficial for eliminating deleterious cells, the tumor suppression function of FHL2 deficiency may be achieved in part through acceleration of cell migration in ApcΔ14/+ mice.

Nevertheless, loss of FHL2 activity is associated with increased epithelial cell migration in intestinal epithelium, which might allow to eliminate more efficiently deleterious cells and reduce the risk of tumorigenesis.

Since some of these proteins are deleterious, cells downregulate this initial response rapidly.

The pore-forming protein perforin is the only component that is absolutely required for the granule-exocytosis pathway that cytotoxic lymphocytes deploy to eliminate deleterious cells.

However, this property of ESCs also poses a unique challenge of having to generate therapeutically efficacious quantity of appropriate cell types without being contaminated by potentially deleterious cell types.

Specific subpopulations of T cells have been implicated in deleterious cell fate pathways, contributing to organ damage [ 70].

It has also been argued that factors secreted by senescent cells elicit deleterious cell nonautonomous effects that alter the tissue microenvironment [ 44].

Apoptosis, originally believed to be a process with only negative effects, now is recognized to balance the beneficial potential of eliminating damaged cells against the pathological effects of deleterious cell death (e.g. neurodegenerative disease) [ 27].

In addition, direct cleavage of caspase-3 by caspase-11 was shown to contribute to deleterious cell death in several animal models of neurodegenerative disease (Hisahara et al., 2001; Kang et al., 2000; Shibata et al., 2000).

This relatively high viability may be a consequence of obtaining protoplasts from young actively growing callus tissue, the reduced duration of exposure to the potentially deleterious cell wall degrading enzyme solution, or a combination of these and other factors.

After spinal cord injury, the deleterious M1 cells dominant the early period, whereas the beneficial M2 cells dominate later.