Sentence examples for deleterious at from inspiring English sources

Many valuable compounds, or the intermediates necessary for their biosynthesis, prove deleterious at the desired production concentrations.

Expression with the X-linked 103Y-Gal4 driver was not deleterious at 25°C.

In this model, a large number of the variations observed would be expected to be deleterious, at least to some extent.

Thus selection to maintain survival should decline with age, favoring pleiotropic alleles that have positive effects at young ages and negative effects at older ages, and allowing alleles that are simply deleterious at old ages to reach a high frequency.

Wild-type Tau4R appeared even more deleterious at lowering protein tau levels, although these would result from more intense neurodegeneration with evident less protein synthesis (Figure 5 upper panels, Figure S4B, utmost right panels).

However, proliferation of MECs can become deleterious at sites of confined CSF space, such as the subarachnoid space of the optic nerve [16], as the width of the subarachnoid space here measures only about 0.3 mm and is further restricted through numerous trabeculae and septa.

However, replication with δ > 0 occurs far more frequently than replication with δ = 0: As much as 99.7% of the replication contains at least one deleterious substitution at d = 5 and λ = 0.307.

This is another example of a biphasic effect of NO, with beneficial effects at low doses and deleterious effects at high doses.

Hormesis is described that a toxic substance or stressor has a stimulatory effect at low doses but a deleterious effects at high doses (Calabrese and Baldwin 2003a, b).

Note that, in CDD and SDM, for low to moderate values (0.0-0.7 0.0-0.7lation at either end results in a similar BER degradation, however, for large values (>0.7), correlation at theithersmittendis significantly moresultsterinus than at the receiver.

Likewise, nimodipine (the subject of recent trials in AD patients) provided intermediate protection, supporting ∼60% survival at 10 μM, but also had considerable deleterious effects at higher concentrations.