Sentence examples for deleterious activities from inspiring English sources
In this study we observed direct interaction of epiretinal T-cells with activated tissue microglia, similar to our earlier observations in human eye donor tissue [ 17], and it is possible that the neurodegenerative effect is due to the deleterious activities of microglia that become activated due to T-cell signaling.
The truncated isoform found in 4T1-derived tumors could potentially create a protein with deleterious activities.
However, free haem can display both protective [26], [27], [28] and deleterious activities [29], [30].
Since bacterial plant pathogens rely on quorum sensing mechanisms to infect plants [ 45], a study of A. amazonense homoserine lactonase activity on the deleterious activities of these pathogens would be relevant.
Furthermore, Goldberg and coworkers have shown that among the deleterious activities of TNF- α within the wound is to suppress α-SMA expression in human dermal fibroblasts [ 94]. Figure 5 integrates the cascade of deleterious factors that impact on diabetic granulation tissue onset.
Deleterious activities attributed to these disease proteins is linked with an ability to produce oxidative stress, and also to form oligomers and aggregates in brain, muscle, and lens, as well as pancreas during onset and progression of Type II diabetes [ 20- 25].
Certain physiological traits (i.e., exopolysaccharides and hydrogen cyanide production) were good indicators of deleterious activity of rhizobacteria.
Together, these results show that AID haploinsufficiency is also revealed in its deleterious activity as promoter of illegitimate chromosome fusions.
We hypothesized that limiting physiological AID expression levels could provide an additional mechanism to restrict its deleterious activity.
The deleterious activity of HSP90 in cystic fibrosis is thought to be due to HSP90 sequestration of a hypomorphic CFTR.
This deleterious activity of Rad51p is also intriguing because a number of studies have shown that RAD51 expression is up-regulated in tumor cells (Klein, 2008).
