Sentence examples for deleterious 1 from inspiring English sources

We first examined the DFEs distinguishing between nearly neutral (Ne s < 1), mildly deleterious (1 < Ne s < 10), deleterious (10 < Ne s < 100), and very deleterious (N es > 100) mutations (Keightley and Eyre-Walker 2007).

aSIFT predictions miss 63 mutations in TS270 (58 deleterious and 5 benign) and 9 mutations in CS30 (8 deleterious and 1 benign).

However, free haem can display both protective [26], [27], [28] and deleterious activities [29], [30].

Removal of TNF-α by TNF-α receptor was hypothesized to be potentially deleterious [15].

Dilution of deleterious PIF1 of SeThpif2+ by the pif1 deletion genotypes, SeThpif2-, was the key for this enhanced activity.

Intradialytic hypotension is obviously deleterious [9] and alters renal recovery in patients with acute renal failure [10, 11].

It was hypothesized that removal of TNF-α by TNF-α receptor could have been deleterious [15].

Four lesser deleterious LATS2 mutations were found in LCD2, which contains the phosphorylation sites S408 and S446 by Chk1/2 in response to UV damage (Okada et al., 2011).

The conditional deficiency hypothesis of glutamine has been challenged [12], and it has been suggested that interfering with a potential adaption could be deleterious [3].

Moreover, in some patients, inspiratory efforts could lead to global or regional increases in transpulmonary pressure that can be deleterious [53].

There are altogether 19 variations for this gene out of which 3 are deleterious, 7 are benign and the rest do not have any prediction regarding the outcome.