Sentence examples for deleted mutant of from inspiring English sources

Initial in vivo stability as well as ex vivo biodistribution studies demonstrated excellent in vivo stability of the tracer and uptake in NSCLC xenografted mice, although no large differences with regard to uptake between wild-type (WT) and the exon 19 deleted mutant of EGFR were observed in ex vivo biodistribution studies, therefore necessitating further PET studies described in this work [21].

PK 11195 had no effect on the cytotoxicity of this oprF deleted mutant of P. fluorescens.

Further analysis of transgenic mice carrying WT or a kinase domain deleted mutant of Itk in a T cell specific fashion illustrates that kinase activity of Itk is required for efficient development of these T cells.

In order to develop a safe and immunogenic vaccine, the immunogenicity and protective efficacy of S06004ΔSPI2, a Salmonella pathogenicity island 2 (SPI2) deleted mutant of S. Pullorum was evaluated in 2-day old chickens.

S06004ΔSPI2 (Nalr, the whole SPI2 (~40 kb) deleted mutant of S. Pullorum S06004), constructed using the one-step inactivation method described by Datsenko and Wanner [ 17, 18], was used as the vaccine candidate for this study.

A deleted mutants of the motor domain of this protein, consequently affects the dynamics of recycling endosomes [33] and of their content, such as the reporter protein followed in this study.

Constructs with deleting mutants of both GRP78 and AKT will be required to identify the amino acid sequences involved in the binding in the future studies.

To verify whether the SCCmec type-III including the fudoh gene suppresses the colony spreading, we examined the colony spreading of the type-III SCCmec-deleted mutants of four clinical isolates 86/560, 86/961, 86/2652, and 85/3566 [16].

It is difficult to detect a small fraction of deleted mutant genomic DNA in the presence of a vast excess of wild type DNA with array CGH or other popular molecular biology tools [26], [27], [35].

To investigate proliferation in the MOE, wild-type and eNOS deleted mutant mice (3 of each group) were injected with 50 mg BrdU per kg bodyweight.

As examples, we characterized the role of two genes by hemizygote analysis and identified another candidate gene by analysis of the phenotype of a deleted mutant.