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This library allowed the identification of three genes that when deleted lead to increased caspofungin sensitivity SSR1, MID1 and PGA31.
We also identified four genes that when deleted lead to decreased caspofungin sensitivity: DFG5, PHR1, PGA4 and PGA62.
We also identified, for the first time, genes that when deleted lead to decreased caspofungin sensitivity: DFG5, PHR1, PGA4 and PGA62.
In this study, we performed a genetic screen for dominant enhancers of endos and identified several genomic regions that, when deleted, lead to impaired fertility of endos /+ heterozygous females.
This and related effects may explain, at least in part, the striking observation that nearly 300 genes (∼5% of the total genome), when deleted, lead to either an increased or decreased telomere length set-point in yeast (Askree et al, 2004; Gatbonton et al, 2006).
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Indeed, the repression of OsCOI1 expression or the overexpression of OsJAZ8ΔC, in which the Jas domain responsible for JA-dependent OsJAZ8 degradation was deleted, leads to the altered expression of JA-responsive genes and a reduced resistance to Xoo in transgenic rice plants (Yang 2009; Yamada et al. 2012).
A mutation of PLN in which one of the di-arginine residues at positions 13 and 14 was deleted led to a severe, early onset dilated cardiomyopathy.
Recently, a mutation of PLN in which one of the N-terminal di-arginine residues at positions 13 and 14 was deleted led to a severe, early onset dilated cardiomyopathy [4].
One of the strongest genetic associations with autoimmune arthritis in animal models of the disease is the gene Ncf1 that, when deleted, leads to low ROS production and autoimmunity [32], [33].
No item, if deleted led to a substantial increase in alpha.
Brakebusch et al (1999) found that reexpression of integrin β1 in fibroblasts in which the gene had been deleted led to increased integrin α3 and α5 levels.
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