I was there when we started this...Somebody made a few Twitter accounts, we edited Wikipedia, we spammed chat rooms, and we even posted here on Reddit (but it was deleted for lack of evidence).
One goal, "Avoid the costs of having additional treatments", was deleted for lack of content validity -- only 5.4% of respondents selected it in their top three, and its selection did not vary by treatment.
The DelN1HpDnaB deletion mutant (1- 66 residues deleted), which lacks the NTD but consists of an intact α-helical hairpin and the DelN2HpDnaB deletion mutant(1 133 residues deleted), which lacks the first helix from α-helical hairpin and the NTD show 20% and 30% reduction in helicase activity respectively.
ΔGBD/ΔDAD, doubly deleted mDia1 lacking both GBD and DAD.
Consensus sequences were also used as queries in a MEGABLAST search against the 20 Drosophila genomes to precisely determine copy numbers and copy ends (including truncated or deleted copies lacking recognizable conserved protein motifs).
In plants PVX has been utilized as a full-length expression vector capable of infecting distal tissues [ 18- 20] as well as a deleted vector lacking viral genes essential for local and systemic movement [ 21].
Although full-length BTG3 significantly inhibited AKT activation, the BTG3-d4 mutant (amino acids 147 252 deleted) that lacks the AKT interaction domain could not, suggesting that direct interaction is required for the inhibition.
In the case of PfI2, when deleted PfI2 (PfI2(19–144)) lacking KTISW or mutated PfI2 (PfI2W16A or PfI2Y103A) were microinjected, no GVBD was observed, demonstrating the importance of both PfPP1 binding sites in the functional capacity of PfI2.
[material deleted] The lack of in-country human intelligence collection assets contributed to this collection gap.
Lin and colleagues reported that cells deleted for Sir2 lack this phenotype [40], [41].
Thirty-one items were deleted due to lack of fit or differential item functioning.
