Exact(1)
WT ICP27 and deletion mutants DΔS5, S5, Δ26-101 and H17 were seen to bind to GST-Hsc70; however, ΔN, in which amino acids 3 to 28 are deleted, and ΔC, in which residues 450 to 512 are deleted, failed to bind to Hsc70 (Figure 2A).
Similar(59)
Cells in which the gene encoding Cdk8 has been deleted fail to enter aggregates due to a failure of early gene expression.
In addition, mice in which the integrin αvβ6 is deleted fail to activate TGF-β (transforming growth factor-β) and develop age-related emphysema which is prevented in MMP-12−/− mice and by overexpression of TGF-β1 [ 69].
In contrast, the C-terminal tagged genes and all N-glycosylation sites deleted gene failed to direct the secretion of functional hFasLECD.
8– 9 In line with these results, human TRF1 is required for the efficient semi-conservative replication of ds telomere DNA. 10 When TRF1 was conditionally deleted, cells failed to replicate telomere DNA efficiently, leading to the activation of ATR, a sensor kinase monitoring ssDNA generated by replication stalling.
The White House has threatened to veto the measure if the provision remains in it, but an effort to delete it failed today on a 224-to-163 vote.
Sirt1 has been implicated in CR-induced lifespan extension in mice because Sirt1 gene deleted mice fail to display at least some of the phenotypes of CR mice [ 53], the most important of which is failure of CR to extend lifespan [ 54].
Primary TAK1flox/flox MEFs were also infected with Cre recombinase protein but TAK1 deleted primary MEFs failed to grow.
We found that UAS-endoAΔLQPNP, in which the homologous five residues of dEndoA-BAR were deleted (Figure 1A), failed to rescue the development of endoA nulls to adulthood (Figure 2).
In embryos with the talin gene completely deleted (Δtalin), 38% failed to undergo GBR, showing that talin makes an important contribution to this process, but there must be a compensating factor that allows many embryos lacking talin to undergo GBR.
Some of my friends speak of deleting tweets that failed to garner attention.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com