Exact(1)
We therefore generated a suicide vector designed to delete the promoter and open reading frame of dapA in Yersinia pestis, which is predicted to delete the expression of two genes, dapA and nlpB (dapX), likely present in an operon (Figure 1A).
Similar(59)
If rcpA is deleted, the expression of RcpB decreases moderately and RcpC slightly [15].
This introduced multiple stop codons in the reading frame of env after the end of vpu reading frame, and deleted the expression of env.
In cells in which the AIM24 gene was deleted, the expression of MICOS subunits was altered.
That's the fascination of notebooks and letters, of early drafts and sketches, discarded shards and deleted scenes — the expression of the spirit is everywhere and mercurially rapid; every stroke of creation is instantaneous (and a definition of criticism is a differential calculus for the instant of creation).
CD11b positive microglial cells and three-fold increased expression of mRNAs coding for the chemokine MIP1α were observed at 10 days in the brain cortex of MPSIIIB mice, but not in MPSIIIB mice deleted for the expression of Toll-like receptor 4 or the adaptor protein MyD88, indicating early priming of microglial cells by heparan sulfate oligosaccharides in the MPSIIIB mouse brain.
Unexpectedly, PfI3 strongly increased PfPP1 activity in vitro and was unable to rescue yeast deleted for the expression of its ortholog.
To test this hypothesis, we generated mice heterozygous or homozygous for pancreas-specific knockout of Bmpr1a (referred hereafter as pBmpr1aHet or pBmpr1aKO) in which the floxed Bmpr1a sequence was deleted by the expression of Cre transgene under the control of the promoter for Pdx1 (the pancreas and duodenum transcription factor 1, also in humans called IPF1 or IDX1) gene.
Similarly, in the Ihh-deleted mice, the expression of Gli1, Gli2, type X collagen, MMP-13 and Runx2 were decreased and aggrecan and type II collagen were increased.
The results of the study showed that when ace3 was deleted or over-expressed, the expression of xyr1 was altered, suggesting that ACE3 could be a major regulator in T. reesei (Hakkinen et al. 2014).
Contrary to previous designs to analyze HIV-1 fitness, these replication competent viruses were created in an intact viral genetic background (without deleting or affecting the expression of any viral gene).
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