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This indicates that the phenotypic overlap between MMP-13 and uPA causing a delay in wound healing also causes a delayed turnover of the epidermis posthealing.
Delayed turnover in patient cells resulted in an increase in the number of clathrin puncta (mRFP-tagged CLC) that were positive for GFP-OCRLD523G at any given time.
In our experience, this possible technical pitfall is not clearly stated in the instruction manual of the instrument and may cause poor tissue processing due to delayed turnover and discarding of alcohol.
The results of this analysis, shown in Figure 4A-C, are consistent with our previous observations indicating that the lack of OCRL in patient cells leads to a delayed turnover and extended CCPs lifetime.
Similar(56)
Deregulated Abl kinase shared with IL-3 the ability to delay turnover of transcripts involved in proliferation or differentiation blockade, relying, in part, on signaling through the Mek/Erk pathway.
The trustee, George A. McLean Jr., said he delayed the turnover because the parties were in new settlement talks.
Knocking down NHERF1 expression in Zr75.1 cells markedly delayed the turnover of PDGF-induced phospho-Akt.
Indeed, RanBP9 siRNA and overexpression markedly accelerated and delayed the turnover of SSH1, respectively, confirming that RanBP9 positively regulates SSH1 protein stability.
Effect compartment models are perhaps better suited to relatively short delays; turnover models may favor longer delays.
In "Time delays between plasma concentration and response," three classes of PD model are described: distributional delay, turnover delay (aka indirect response), and receptor on/off.
If delaying the turnover a few weeks would allow a more democratic transition, the U.N. should consider stretching out the timetable.
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