Sentence examples for delayed replication from inspiring English sources

Altogether these observations clearly indicate that a common feature of CFS is delayed replication, substantiating the hypothesis that CFS are regions intrinsically difficult to replicate.

These results suggested that the silencing of RBM24 stimulated the initial translation of HCV proteins but inhibited and delayed replication of HCV genome.

It is generally agreed that fragile sites comprise regions of high DNA flexibility and display delayed replication [12], [13].

In particular, this is presumably the case for origins that show delayed replication due to the chromatin state of the chromosomes [27] or to the Cdk1-Clb5 activity [43], [44].

Also, ECs cultured in HG show delayed replication, abnormal cell cycling, and increased apoptosis.

Acquired chromosomal rearrangements in human cancers have been associated with delayed mitotic condensation, delayed replication timing and mitotic instability (30).

Therefore, by delaying replication, Hog1 plays a key role in preventing conflicts between RNA and DNA polymerases.

When yeast cells are stressed during S phase, Hog1 promotes gene induction and, remarkably, also delays replication by directly affecting early origin firing and fork progression.

For example, within a minute or two of damage being inflicted on the genotype by ionising radiation H2AX labelling occurs at damage sites, checkpoints are instigated to delay replication and macroscopically discernable foci of proteins assemble around the break [34] [36] but it is not until tens of minutes later that the system responds with transcriptional responses [37].

It is possible that deletion of ARS607 did not significantly delay replication timing in the region.

Thus, delaying replication in response to osmostress must be important both to provide proper adaptive gene expression and to prevent genomic instability.