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Signs may include delayed relaxation of the ankle reflex and a slow heart beat.
Hypothyroid wild type mice show delayed diastolic cardiac relaxation or delayed relaxation of papillary muscle.
Cardiomyocytes demonstrate both impaired contractility and delayed relaxation in mice models of DCM as well [ 34, 35].
It was hypothesized that postural functions of the PFMs could play a role in voluntary contractions and delayed relaxation [ 29].
The observed muscular stiffness in PMT is due to a delayed relaxation of muscles of the fast twitch (type II) fibers.
However, subsequent studies consistently observed that the decay phase of the calcium transient was prolonged in mdx muscle fibers, consistent with the profile of delayed relaxation observed in intact muscle.
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Four other eat-6 mutations were initially isolated for feeble contractions and delayed relaxations of the pharyngeal muscles [9], and subsequently shown to affect the membrane potential of these cells [10].
Myotonia Congenita (MC) is a nondystrophic skeletal muscle disease characterized by muscle stiffness, weakness, delayed skeletal relaxation and hypertrophic muscle.
Both hypothyroidism and heart failure result in delayed diastolic relaxation and abnormal calcium handling.
Approximately two-thirds of the cohort exhibited TDI evidence of delayed myocardial relaxation (E' < 9.6 cm/s).
Placement of active patches causes a small, delayed microvascular relaxation in healthy subjects at room temperature.
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CEO of Professional Science Editing for Scientists @ prosciediting.com