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Maps are displayed separately for immediate and delayed recollection.
One question involves the role of the PRC and PHC in immediate and delayed recollection.
DOI: http://dx.doi.org/10.7554/eLife.05025.013 Results from these univariate analyses indicate that differences in brain activity associated with immediate and delayed recollection varied across MTL subregions.
The reviewer expressed a concern that the difference in posterior hippocampal activation between the immediate and delayed recollection contrasts could be driven by differences in response times (RT).
In our original submission, we used the term "delay-invariance" to refer to regions that did not significantly differ in their contributions to immediate and delayed recollection.
The absence of a clear main effect or interaction may be due, in part, to substantial variability in context similarity effects during delayed recollection.
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DOI: http://dx.doi.org/10.7554/eLife.05025.012 10.7554/eLiFigure25.013 figure 3—figure supplement 2. Conjunction of immediate and delayed recollection-related activity.
Peaks are reported in Supplementary file 2. The conjunction of immediate and delayed recollection-related activity is shown in Figure 3 figure supplement 2. DOI: http://dx.doi.org/10.7554/eLife.05025.010 10.7554/eLiFigure25.011 Figure 3 source data 1.
The goal of the present study was to use fMRI to examine changes in MTL activity during immediate and delayed item recollection.
Whereas posterior HF showed reduced recollection-related activity after a 1-day delay, recollection-related activity in anterior HF remained relatively stable.
Beyond the MTL, across both delays, recollection-related activity was also observed in a network of regions including the retrosplenial cortex, posterior cingulate, precuneus, angular gyrus, and medial prefrontal cortex.
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