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If diagnosis tends to be delayed over time until patients have reached a more severe stage of the disease, then age-specific diagnosis rates would decline.
For Poisson regression, the unconstrained distributed lag model may be written as Log(μ t) = α + COVs + β0 Z t + β1 Z t – 1 + … + β j Z t – q, [1] where COVs represents all other covariates in the model, and Z t represents cold-spell exposure delayed over time for j = 0 … q days.
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In a phenological study of twelve plant and animal taxa in Japan and South Korea, first observations of a five of these species (frog, butterfly, wasp, and two bird species) were delayed over the time period of 1953 2005 at the majority of sites [29].
Flights delayed over 80percentt of the time would need to be scheduled accurately or wouldn't be flown.
She said: "We inherited a much worse situation with people delayed over four weeks being three times what it is now.
TB control programmes may need to monitor treatment delay over time.
Similar to findings in our study, a shortened diagnostic delay over time was found in the UK [ 5], but was not observed in Canada [ 4].
Change in delay over time is rarely reported and our prospectively followed TB cohort gives an opportunity to present such data.
The aim of this study was to describe risk factors for treatment delay, to assess the possible effects of treatment delay on clinical severity at diagnosis and to monitor changes in delay over time in a prospective TB programme.
Also, we did not study the improvement of delays over time, and it is not fully clear which of those represent just a variation of individual development and which some form of a permanent pathology.
Animals receiving GD2-targeted T-cell therapy had lower numbers of pulmonary tumours than controls, and the median volume of soft tissue tumours at first detection was lower, with a tumour growth delay over time.
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