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A design method presented in a previous paper for the sequential generation of observation sites used for the inversion of a prediction model is extended to cope with practical issues such as delayed observations and design of batches of imposed size.
An immediate consequence of delayed observations is that patients may withdraw or become lost-to-follow-up before their outcome is observed.
Another consequence of delayed observations is that interim analyses cannot take place as soon as the required sample size has been recruited and randomised.
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Indeed, following [5, 8], the time differences corresponding to the th up and down link delay observations of the th timing message exchange can be expressed respectively as and, respectively.
When compared with the kinetics of the anti-PPV response, the development of the anti-PCV2 Ab appeared to be delayed, an observation also made by others [ 28].
Moreover, any adhesion between the plasma membrane and the cell wall would delay the observation of plasmolysis.
The POD of Chang'E-1 is performed using S-band two-way Range and Range Rate (R&RR) data, together with VLBI delay and delay rate observations.
However, these patients usually have a disability and/or poor verbal communication skills, and thus, the detection of pain or adverse events associated with epidural catheterization (especially epidural hematoma) might be delayed, and vigilant observation and comprehensive management are required to prevent such events.
The important observations include; delayed DNB in case of nano fluids as compared to de-ionized water.
Although all the travel times were slightly delayed compared to the observations (red lines), the P PHS and Pn phases and their transition at epicentral distance of 180 km were clearly found along the X X′ profile (top panel of Fig. 4a).
Similar observations like delayed, reduced or even failing antibody response are reported for hemorrhagic-type smallpox patients [38].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com