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Another delay was the modification of the armour plates with tongue and groove joints to lock the plates together and increase their resistance to armour-piercing shells.
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Dose modification and delay was permitted in the event of some treatment-related side effects.
In case of G1 toxicity or first occurrence of G2 toxicity lasting <7 days, no dose modification or delay was planned.
The delay was understandable.
But the delay was frustrating.
Dose modification or treatment delay was not necessary.
No dose modification or any delay was necessary to manage toxicity.
Tumour blood flow was increased by 30% after a flunarizine dose of 4 mg kg-1, but no modification in growth delay was induced by melphalan (12 mg kg-1).
Decisions about dose modification and/or treatment delay were left to the discretion of the local practice.
5percentt as the cutoff for dose reduction and 10 days as the cutoff for the delay were defined because such were minimal modifications observed in our study.
The modifications aren't going very well.
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