Across single-subject analyses and two different group analyses, the Frontal Eye Fields (FEF), Supplementary Eye Fields, and Intraparietal Sulcus were most reliably found to support multi-delay sustained activity, and effects tended to be more robust in left than right hemisphere.
Electrospun polymer-based fibers have been investigated for providing different types of controlled drug release profiles, such as immediate, delayed, sustained, and biphasic releases [7, 8].
The FDA database is using the term extended release for all modified release forms such as delayed, sustained, pulsed release.
Consumption of ≥75 g of protein resulted in a significantly delayed, sustained, elevated, postprandial glycaemic excursion from 180 to 300 min compared with a control drink (water).
In a subsequent study using variable delay durations, sustained posterior gamma components were described which, however, also showed a constant power decrease over time (Tallon-Baudry et al. 1999).
Furthermore, Tmax (24 h or greater) was delayed compared with that of total plasma Pt or gel-filterable Pt, suggesting that NC-6004 provides a delayed and sustained release of potentially active Pt species after the administration period.
Asacol® 400 mg and Asacol® 800 mg (Asacol® HD) and the new generation, high dose (1200 mg) delayed and sustained release formulation, Mezavant® (Lialda®), are compared in pH 7.4 Krebs bicarbonate and phosphate buffers.
Whereas Tat caused rapid phosphorylation of JNK, morphine caused a more delayed but sustained JNK activation (Figure S1C).
In contrast to the rapid drop observed during endotoxic shock, the drop in MABP of endotoxemic mice injected with PAF was delayed and sustained at near normal levels for at least 5 h (Figure 3D).
In both clusters, TR displays a strong upregulation upon stress; yet while there is a delayed but sustained increase of RA in cluster 11 (enriched in the 'Proteasome complex' and 'Endoplasmic reticulum' GO categories, see below), the RA increase in cluster 12 is faster and stronger.
For instance, materials have been investigated that generate "burst", "delayed", or "sustained" release characteristics.
