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This was done by assessing the delay of emergence of malaria parasites in the blood after a radical cure, such a delay denoting an alteration in hepatocyte receptivity to the parasite [11], [12].
For example, EINUM and FLEMING [ 19] showed that the delay of emergence of one standard deviation (SD) resulted in a 39% increase in mortality, while 1 SD decrease in length at emergence resulted in a 25% increase in mortality during a 17 day period in the natural environment.
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Another important goal for chemoprevention is the maintenance of an androgen-sensitive clinical state and delay of the emergence of androgen independence.
In the initial model this probability was 69% for those diagnosed through screening (compared with 59% for those diagnosed symptomatically) resulting in a delay of the emergence of symptoms of 6 months.
Forty-two patients (84%) required reversal of rocuronium using sugammadex sodium, and eight patients (16%) were given naloxone because of delayed emergence of spontaneous breathing.
The trade-offs that occur between parasitic and saprophytic phases of the life cycle may prevent or delay the emergence of high levels of pathogen virulence.
This is because in this model the main effect of early diagnosis is to delay the emergence of symptoms, but the progression of disease thereafter is the same under the late and early diagnosis assumptions.
Initial experiments using the model suggest that a single anthelmintic treatment, administered soon after patency of initial infection, may effectively control environmental contamination with Parascaris spp. eggs while allowing a small 'refugia' of susceptibility to delay the emergence of anthelmintic resistance.
The approach of limiting prophylaxis to a subgroup of patients with the highest risk of candidemia may help to limit the quantity of antifungals used and delay the emergence of infections due to fluconazole-resistant Candida strains seen in immunocompromised patients.
For many years until now, combination therapy with two or more antibiotics is used in special cases to prevent or delay the emergence of resistant strain, to treat emergency case during the process of diagnosis, and to take advantage of antibiotic synergism [ 14].
It is important to conduct HIV DR surveys to estimate the TDR rate among ART-naive populations with different transmission routes to provide baseline information for the formulation of effective ART regimens to delay the emergence of DR and to develop a rational public health strategy to control the HIV epidemic.
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CEO of Professional Science Editing for Scientists @ prosciediting.com