This agrees with other reports of delayed escalation in therapy (clinical inertia) and clinical assessments not translated into actions to improve control (9).
The belated handover of the black box belonging to flight MH17 is likely to delay the escalation of economic sanctions against Russia.
In fed-batch bioreactor cultures, the engineered cell lines exhibited a more gradual viability loss and extension of culture times of 36 72 h, with corresponding delays in escalation of caspases 2, 3, 8 and 9 activities, compared to the control cultures utilizing cells transfected with the vector backbone.
In addition, we assumed that any changes to patient therapy will be similar in UMEC/VI and tiotropium treatment arms such that there will be no additional benefit of UMEC/VI in delaying treatment escalation.
Last week the National Audit Office published a rexport that found there had been significant delay and cost escalation to 12 of the 14 large projects at Sellafield.
5. If, in the meantime, oil does rise to $75/barrel in a year or two, the slack now available to producers will delay any sudden escalation, for OPEC can increase production as necessary.
Whereas clinical inertia of physicians might delay commencement or escalation of therapy (18), frequent testing of risk factors may not translate to changes in treatment regimens (19).
"Delayed partly for political reasons in 2010, it is now becoming clear that further slippage in the programme has been down to poor management, significant cost escalation, delays in the construction of the Astute [nuclear-powerd but conventionmally armed] attack submarines at Barrow, and other uncertainties", says BASIC's executive director, Paul Ingram.
For nuclear power to play a major role in meeting the future global energy needs and mitigating the threat of climate change, the hazards of another Fukushima and the construction delays and costs escalation that have plagued the industry will have to be substantially reduced.
Moreover, delay in de-escalation might be considered long (3.5 ± 0.7 days) with respect to the current guidelines (two to three days) [ 8], but maybe not in respect to clinical practice [ 10].
