Sentence examples for degrees of malignancy from inspiring English sources
In this study, we investigated the impact of hypoxia on cancer progression using a panel of breast cell lines with different degrees of malignancy, namely the non-malignant breast cell line MCF-10A and the two breast carcinoma cell lines MCF-7 and MDA-MB-231.
At the protein level, we have shown that in the MCF10-system of genetically related cell lines of differing degrees of malignancy, Smad4 levels were higher in non-malignant MCF10A cells than in the increasingly malignant cell lines MCF10At1k.cl2, MCF10CA1h, and MCF10CA1a, indicating that decreased Smad4 protein expression might accompany tumor progression from early stages on in-situ and in-vivo.
In this work, a panel of breast cell lines with different degrees of malignancy was used to study how hypoxia affect cells depending on their stages of cancer progression.
Therefore, long-term hypoxia seems to reduce the differences previously observed with short durations of hypoxia among cell lines with different degrees of malignancy in that metastatic cell lines show, or begin to show, similar sensitivity to that of non-metastatic breast cells.
Atypical proliferates eventually form gross tumors with varying degrees of malignancy by postnatal day 350.
These are then graded into 4 histological degrees of malignancy, according to the WHO classification [ 1].
To address these problems, we developed a novel hyperspectral imaging (HSI) system based on laser-induced synchronous fluorescence for rapid, non-invasive, in vivo identification and characterization of various degrees of malignancies in the GI tract.
When examining clinical urine specimens, Gupta et al. discovered that cannibalistic activity, degree of malignancy and metastatic potential of malignant cells were closely related.
Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas.
A majority of malignant tumours express MMP2; the expression of which is associated with the degree of malignancy, tumour angiogenesis, invasiveness and metastasis [ 9– 14].
