Neuroendocrine tumours may manifest at different degrees of differentiation, from well-differentiated (carcinoids) to poorly differentiated, or anaplastic or somatic/neuroendocrine mixed forms.
Between January 1999 and November 2003, 27 patients with histological diagnoses of endocrine tumours with different degrees of differentiation, excluding well differentiated carcinoid neoplasms, received intravenous (i.v).v
Adenocarcinomas displayed variable degrees of differentiation, ranging from well to poorly differentiated, with a tendency to form disorganized and cribrose acinar-like pseudocrypts that penetrated deep into the lamina propria, in the absence of an interceding basement membrane.
The abdominal muscles show increasing degrees of differentiation in the fully metamorphosed, more derived taxa.
The aspect ratios of partially- or fully-reprogrammed iPSCs (e,f) or ESCs with distinct degrees of differentiation (g) were calculated as indicated in (a).
Brown frogs of the complex Rana macrocnemis demonstrate various degrees of differentiation between the two widespread forms, macrocnemis and camerani, in different parts of Anatolia, the Caucasus Isthmus and northern Iran.
For every level of differentiation, there exists a minimum level of integration below which the system would disintegrate into chaos and the higher levels of integration require higher degrees of differentiation in order to avoid sterility.
Having a series of stages also allows for degrees of differentiation within a connected whole.
Lobules were separated by fibrous septa and were composed of mature adipocytes and vacuolated lipoblasts showing varying degrees of differentiation.
These trends (solid lines in Figure 7) are consistent with those of granitic rocks, suggesting that the chemical variations of these samples are largely inherited from the granitic source rocks, but with variable degrees of differentiation.
Importantly, an examination of "stemness" genes identified a continuous, rather than discrete, stemness-related gene expression signature among individual glioblastoma cells, which suggests that glioblastomas contain primitive populations of stem-like cells with variable degrees of differentiation and proliferative capacity.
