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Our data contain a degree of heterogeneity with different degrees of bone formation among animals, most likely due to the local individual host response.
At six weeks, the untreated surfaces presented lower degrees of bone formation in proximity to the implant surface and 6(F)) relative to their APP-treated counterparts and 6(h)).
The histological evaluation revealed that the interaction between tissue and implant surface occurred at three weeks in vivo for both experimental groups (APP-treated CaP and APP-treated Ti), while the untreated CaP and Ti groups displayed lower degrees of bone formation in proximity to the implant surface interaction until six weeks in vivo.
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The Gore-Tex group showed good bone formation, whereas the Vicryl group showed the highest degree of bone formation.
Hydroxyapatite-coated titanium wires showed the highest degree of bone formation around them and greater pull-off strength.
Two independent investigators masked to the groups of cells estimated the degree of bone formation using a semi-quantitative scale as previously described [23].
After menopause, the amount of bone resorption by osteophages is greater than the degree of bone formation by osteoblasts.
The ratings for each sub-item were given according to the degree of bone formation and union.
The μCT analysis correlated with the assignment of histological scores to the degree of bone formation in implants of HA/TCP, loaded with human BMSCs.
Instead of a comparable degree of bone formation and resorption, there is decreased bone formation (osteoblastic activity) and increased bone resorption (osteoclastic activity).
Their APP-treated counterparts, however, presented a more well-distributed bone formation within the plateau and a higher degree of bone formation in proximity to the implant surface and 6(d)).
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