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A good relationship was shown between the degree of superimposition and the inhibitory activity, except in one case, implying that candidate haptens can be computationally selected.
The in vivo in silico simulation using physiologically based pharmacokinetics (PBPK) model and population simulation (100 subjects) revealed a reasonable degree of superimposition of simulated and observed pharmacokinetic parameters based on overall fold error (≤2.0).
While in panel A the blue and the red peaks clearly alternate, in panel B the trend is less clear, showing some degree of superimposition of the two traces during some of the trials.
This analysis revealed a strong but comparable degree of superimposition of the origins of projections directed to CAC and PMd, CAC and PMv, RAC and PMd, and RAC and PMv, ranging from 14%to20%0%.
As previously reported (Tanné-Gariépy, Boussaoud, and Rouiller 2002; Morel et al. 2005; Cappe, Morel, and Rouiller 2007), we quantified the degree of superimposition between the origins of projections by taking 2 by 2 the different combinations of retrograde tracers, using an index of overlap.
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Even though fluoroscopy has not yet been applied to the elbow, this joint is of particular interest for its validation because it is characterized by (i) a high degree of bone superimposition, (ii) being composed by thin long bones (in contrast with the typical morphology of knee prosthesis), and (iii) marked longitudinal cylindrical symmetries (especially for the radius).
However, by reducing the degree of tissue overlap and superimposition of structures, slight differences in contrast and subtle morphologic disruption of tissue due to malignancy are more conspicuous and result in improved detection of all invasive breast cancers, and may prove particularly useful for detecting ILC.
Keen used highly innovative techniques of superimposition and editing, and frequently etched and degraded the film surface.
CM stimuli led to greater proportions and longer periods of superimposition.
The method of superimposition is taken from Procrustes.
CBCT also eliminates the problem of superimposition of roots by surrounding anatomical structures.
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degree of redundancy
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