The high degree of sequence divergence in these divergent regions compromises alignment of short reads.
By comparing the degree of sequence divergence between modern Eurasians and Neanderthals and the degree of sequence divergence between two independent Neanderthal samples derived from different archaeological sites, the researchers were able to estimate that as much as 1 4% of the genome sequence in modern Eurasians might be traced to Neanderthals.
DNA shuffling has been extended to distantly or completely unrelated gene families, which require methods that do not rely on homologous recombination because of the degree of sequence divergence.
The high degree of sequence divergence among several lineages suggests that multiple Ligia species exist.
We targeted two HvmALP isoforms displaying the highest degree of sequence divergence (6%) of all the described HvmALP isoforms [34]: Hvmand1 (FJ416470) and HvmALP2 (FJ416471).
Alignment analysis of the T. castaneum chemoreceptor gene family (TcasGr and TcasOr) indicated that the family members share a high degree of sequence divergence (Figure S1C, S1D).
Our estimates of the divergence time of the two haplotype clades in great reed warblers range from 18 kyr BP with the IMa method to 65 87 kyr BP based the degree of sequence divergence.
Despite the fact that TAAs perform an important role in host cell infection, it appears that they have evolved with a high degree of sequence divergence and general architecture as a means to escape host immune response.
This analysis suggests that despite the large degree of sequence divergence in a majority of fold families, atomic interactions between amino acids in the solvent-unexposed core of domains (PCAINs) are a highly fold-conserved feature.
Despite the high degree of sequence divergence, the predicted secondary structure of the NVAV nucleocapsid protein exhibited the characteristic coiled-coil domains at the amino-terminal end, and the L-segment motifs, typically found in hantaviruses, were well conserved.
The degree of sequence divergence compared with isolates of O. tsutsugamushi was substantial, averaging >17% (5 ).
