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Approximately 40 60% of LARC patients treated with neoadjuvant CRT achieve some degree of pathologic response.
However, a positive correlation was found between the degree of pathologic change and expression levels of cFLIP protein and mRNA.
Approximately 40 60% of rectal cancer patients treated with neoadjuvant chemoradiation achieve some degree of pathologic response.
Inflammation and erosion of the cartilage were observed in sections from the nose, trachea, and larynx, and the degree of pathologic changes was correlated with clinical scores.
63, 64 The degree of pathologic changes correlates with clinical pain scores 15, 65 and may predict worsening of symptoms in the next 1 2 years.
They are the so-called site-specific factors including tumor deposits, the tumor regression grade, which determines the degree of pathologic response to neoadjuvant treatment, the CRM, microsatellite instability, perineural invasion and KRAS mutation status.
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11 The prevalence of greater degrees of pathologic necrosis in this study may have been the result of twice-daily (total dose 4770 cGy) fractionation in a substantial percentage of patients.
On the contrary, Stadlbauer et al. reported a negative correlation between FA and glioma cellularity, however the authors concluded that FA is a better indicator than MD for the assessment and delineation of different degrees of pathologic changes in gliomas [ 53].
Therefore, loss of nuclear TPPP immunoreactivity appears to correlate with the degree of oligodendroglial pathologic changes.
In addition, eradicative degree of surgery, pathologic stage, depth of tumor invasion and location of tumor were identified as independent prognostic factors of patients with GC as well.
Eradicative degree of surgery, pathologic stage, depth of tumor invasion and location of tumor were also identified as independent prognostic factors found significant.
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