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In clinical practice, pressure measurements, recording drops in pressure across the stenosis, are now being used to determine physiological significance, as the degree of narrowing on imaging can be misleading.
Such a stiffened parenchyma as occurs with whole lung aerosol challenge acts as an increased elastic load on the airways that reduces the degree of narrowing.
Although the airways started out with the same degree of narrowing regardless of the method of stimulation, there were significant differences in how they responded to increasing inflation pressure, depending on the how the histamine was delivered.
Carotid stenosis was defined as any degree of narrowing in either the internal, external or common carotid arteries by carotid plaques.
None of these studies demonstrated a clear association between the degree of narrowing and clinical symptoms nor could cutoff values be determined.
However, at the onset of mitotic rounding of the transcellular lumen compartment collapsed, while the proximal multicellular luminal compartment appeared unchanged, apart from a degree of narrowing (Fig. 7G,G′).
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Radiation damage to the colon can be shown radiographically as loss of distensibility with strictures of various lengths and degrees of narrowing.
A significant advantage of HRCT in evaluation of tracheobronchial amyloidosis is the ability to accurately assess the degree of luminal narrowing.
Coronary atherosclerosis is less likely to be associated with calcification among women compared with coronary atherosclerosis with a similar degree of lumen narrowing in men [ 30].
Quantitative angiographic scoring was performed using the Gensini score that quantifies CAD severity by a nonlinear points system for degree of luminal narrowing.
The reduced FVC and flows are most likely due to a severe degree of airway narrowing involving small to medium airways that may be accompanied by air trapping, partial closure of airways and elevation in FRC.
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