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The nlBC values modestly correlate with degree (Additional file 3A), whereas the p-value has almost no relationship with degree or nlBC (Additional files 3B and 3C).
This can be reflected by the consistency degree (additional file 3).
Similar trend was observed in the case of Huh7 cells but to a lesser degree (Additional file 4: Figure S10).
Lung cancer was previously underfunded and continues to be so, but to a slightly lesser degree (Additional file 3: Figure S1).
In addition to patient P4, a second leukemic patient (P17, AML, FAB M0) showed no elevation in PLA2R1 methylation (3% methylation degree, Additional file 1: Table S1).
These pairs clearly dominate the joint distribution of the positive interactions, while being supported by the SGA approach to a varying degree (Additional File 4).
Taking the above results together, the findings suggest that VP2-345N, VP2-435N, VP3-246M and VP3-246M all seems to be structurally and antigenically very similar to their native protein, at least to some degree (Additional file 1: Figure S3).
Moreover, PONDR VL3 analysis [ 27, 28] indicated that the C-terminal region of TaNAC29 was intrinsically disordered (ID) to a large degree (Additional file 1: Figure S1C), suggesting that the protein was largely unfolded in the C-terminal region.
Of 79 ribosomal protein mRNAs, all but 10 were significantly increased in the insulin-responsive translatome and only 3Rpl3636, Rpl39 and Rpl7l1) were not upregulated to any degree (Additional file 6).
And, low dose (1 μM) treatment of vorinostat in A549 cells exposed to B[a]P in vitro also inhibited cell proliferation to a similar degree (Additional file 2: Figure S2): the number of viable cells significantly decreased at 72 h (P = 0.01) and 96 h (P = 0.008, Student t-test) after treatment with vorinostat compared to the control.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com