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Thus, our observed improved sensitivity of computed tomography might reflect, to some degree, confounding by severity as these patients might have a larger volume subarachnoid haemorrhage than patients in whom initial assessment and imaging are delayed.
We have performed both unadjusted analyses and analyses adjusted for year and place of birth to determine to which degree confounding underlies our previous results.
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Such patients are likely to have varied presentations of often very advanced or rapidly progressing (and symptomatic) disease, and may, to a degree, confound the findings.
While this approach should yield greater specificity for the pathophysiological process of plaque rupture, the results could still be to a degree confounded by the differences in cell composition between stable and ruptured lesions.
In general, the effect of humanitarian assistance may have to varying degrees confounded the true impact of crises on ARI burden, so that our findings mainly represent burden in settings benefiting from some humanitarian relief.
Any such correlations might "constrain" the ability of the internal marker to reflect the degree of confounding amplification that is influencing the nonincluded confounders.
We varied the degree of confounding across simulated studies.
The difference between the cohort and intersiblings estimates was used as a crude measure of the degree of confounding.
Cage information is displayed below each animal when known and indicates a fair degree of confounding between cages and families.
Because this study incorporated matching for fish intake, it may be affected to a lesser degree by confounding from nutrient intakes.
Although we identified AUROC values that protected against obtaining incorrect results, the accuracy of risk-adjustment necessary depended on the population studied, study size, and degree of confounding.
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CEO of Professional Science Editing for Scientists @ prosciediting.com