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It degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group in both vertebrates and invertebrates (Varo et al. 2008).
This protection lasts even after the zinc layer is scratched but degrades through time as the zinc corrodes away.
Xrn1 degrades through nearly the entire viral gRNA before stalling near the beginning of the 3′UTR; what remains is an sfRNA.
AChE is an enzyme that degrades, through its hydrolytic activity, the neurotransmitter acetylcholine and is critically important for the regulation of neurotransmission at synapses in all areas of the nervous system [ 7].
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Petroleum-based polymers such as polyolefins are degraded through photo-degradation (Kumar et al. 2011; Sen and Raut 2015).
For example, it has been reported that Twist can be degraded through the ubiquitin/proteasome degradation pathway, as treatment with a proteasome inhibitor inhibits degradation of Twist [10].
Free cytosol β-catenin is degraded through ubiquitin-mediated degradation.
Second, they can be degraded through a process called ER-associated degradation (ERAD) (Vembar and Brodsky, 2008).
This protein has been shown to be ubiquitinated for degradation through the proteasome, as well as degraded through chaperone mediated autophagy.
In eukaryotic cells, proteins are degraded through two major proteolysis systems: the proteasome degradation and autophagy.
Although usually degraded through the proteasome, alpha-synuclein requires unfolding for degradation and aggregating forms of this protein may require clearance through other pathways.
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