Sentence examples for degradation machine from inspiring English sources

Recent electron microscopy (EM) studies have allowed major breakthroughs in understanding the architecture of the regulatory particle, revealing that the additional modules provide a structural framework to position critical, ubiquitin-interacting subunits and thus allow the 26S proteasome to function as a universal degradation machine for a wide variety of protein substrates.

Hfq is also required for stabilization of sRNAs by protecting them from RNA degradation machine [ 10].

In summary, the ubiquitin-proteasome pathway is not only a degradation machine focused to destroy old or damaged proteins.

The proteasome is a highly conserved protein degradation machine made up of two complexes: the catalytic 20S proteasome (also called core particle) and the 19S regulatory particle (RP), both of which are composed of a set of multiple distinct subunits (Coux et al., 1996; Schmidt et al., 2005).

In this case, binding of ClpT proteins to the axial pores of the Clp protease would interfere with Hsp100 association and their removal would lead to the completion of the Clp(C/D)/ClpPR degradation machine, as proposed in the earlier model of Peltier et al. Our results add new evidence to the functioning of the Clp complex but also call into question some aspects.

Our results clarify a previously reported paradoxical result in protein nanomechanics and contribute to refining our toolbox for understanding the unfolding mechanism used by translocases and degradation machines.

More evidence for interactions between chaperones and the 26S proteasome has emerged recently, lending support to the notion that protein folding and protein degradation "machines" cooperate in the quality control of cellular proteins.

Proteases are degradation machines that aid in the proper functioning of cells by sustaining the balance between protein synthesis and hydrolysis.

A damaged plasticity model has been used to capture the effect of material degradation under machining.

Although pre-copy is extensively used to migrate memory data of virtual machines, it cannot provide quick migration with low network overhead but leads to large performance degradation of virtual machine services due to the great amount of transferred data during migration.

Prognostics intends to assess and predict the time evolution of machine health degradation so that machine failures can be predicted and prevented.