Sentence examples for degeneration upon from inspiring English sources

Taken together, these results demonstrate that inhibition of mitochondrial fission by Drp1K38A resulted in sustained mitochondrial length, reduced axonal ovoid formation, and less axonal degeneration upon capsaicin treatment.

While the physiological basis for the delayed onset of oocyte degeneration upon germline feminization is unclear, this phenomenon proved useful in that it enabled us to examine oocytes and embryos produced by sacy-1 (tm5503 ) females.

We present the case of a 60-year old female patient who developed paraneoplastic cerebellar degeneration upon locoregional recurrence of a poorly differentiated spindle cell carcinoma of the nasal cavity and paranasal sinus.

The inverse correlation between mitochondrial length and axonal degeneration upon capsaicin treatment suggests that inhibition of mitochondrial fission reduces axonal ovoid formation and axonal degeneration by retaining functional mitochondria upon axonal injury.

The non-cell-autonomous contribution of microglia is evidenced by the morphological and functional amelioration of photoreceptor degeneration upon the genetic ablation of retinal microglia and the molecular inhibition of microglial phagocytosis, indicating that microglial phagocytosis of living rods contributes to inherited photoreceptor degeneration.

Studies intended to demonstrate a slowing of the rate of degeneration, modeled upon clinical trials for ALS, are problematic.

However, discrepancies between the friction coefficients of meniscus devices and native articular cartilage do not inevitably lead to joint degeneration, depending upon the ability of the device to support neotissue formation, including surface lubrication (Bonnevie et al. 2014; Lee et al. 2014).

The lack of sugar modification likely causes a disconnection between myofibers, and the muscle degeneration decreased upon birefringence.

In these cases, degeneration and apoptosis upon infection of neurons and the consequent inflammatory response can occur.

In the present study, no distal degeneration was observed upon direct exposure of lower motor neuron distal axons to the excitotoxic stimulus in vitro, indicating that distal axons from lower motor neurons are not susceptible to direct excitotoxicity.

One of the most well-known theories explaining tissue degeneration and aging upon mitochondrial dysfunction is the free radical theory of aging, which was first proposed by Harman in 1956.