eNOS knockout mice also exhibit reduced Zn2+ release after SAH, which was associated with reduced microthrombi formation and neuronal degeneration in the same experiment.
In their cross-sectional MRI study of asymptomatic young men, Reichenbach et al. (2010) found cam deformity, cartilage damage, and labral degeneration in the same location, the anterosuperior quadrant of the acetabulum.
The histomorphological study by Boos and colleagues showed the NP was more severely degenerated in the same age group than the AF [ 22]; however, our biological findings indicate AF degeneration occurs simultaneously with NP degeneration.
However, axonal degeneration in these same Plp1tg mice has been previously described (Anderson et al., 1998), indicating that the PLP mutation affects neuronal function.
In addition to the black cells in the inner retina, the outer retina showed massive photoreceptor degeneration and the same black cells in the RPE layer.
In fact, some FHM families can present with only cerebellar degeneration or seizures and in the same way several genes, isolated in FHM families, are also involved in other neurological disorders with an autosomal dominant inheritance pattern such as episodic ataxia type 2 and spinocerebellar ataxia type 6 [16, 16].
Once a drug is used for treatment of any one chronic disease, its effect against other diseases (atherosclerosis, cancer, prostate enlargement, osteoporosis, insulin resistance, Alzheimer's and Parkinson's diseases, age-related macular degeneration) may be evaluated in the same group of patients.
Notably, serotonergic ADF neurons represented a sensitive target for Ag NPs in comparison to GABAergic neurons that showed no signs of degeneration under the same conditions.
In contrast, photoreceptor degeneration in mice of the same line kept under standard cyclic lighting had progressed to completion by 7 months, with approximately a single layer of cells remaining (n = 6; data not shown).
Caves with very dirty water and/or copious quantities of bat guano often have fish with less eye degeneration than similarly aged caves in the same area.
Variation in hINSC96Y-induced eye degeneration was comparable to previous measurements in the same lines.
