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These results demonstrate that LRCs retain self-renewal potential in a degenerated environment, similar to that observed in aged muscle (Chakkalakal et al., 2012).
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Álvarez-Caudevilla et al. considered a cooperative reaction-diffusion system in a spatiotemporally degenerate environment [10].
If cells are primed by the degenerating environment present in HD progression but do not have the appropriate signals to proliferate there will be no increase in neurogenesis.
One possible explanation for the increase in neurosphere numbers observed in the 33-week-old HD hippocampus is that the degenerating hippocampal environment present during HD progression may in fact lead to the release of factors in vivo which may help to maintain the stem/progenitor cell pool at its normal adult level, but not allow these cells to actively proliferate.
Blackness, in the course of the eighteenth and nineteenth centuries, became seen as a mere disease, with negroes descended not from Adam or even the fabled "mark of Cain" but degenerated from corrupted environment, atavistic savagery, or worse.
Security in Basra, which initially provided troops with a benign environment, might not have degenerated if aid had got in quicker.
Public hospitals have degenerated.
But they've degenerated quickly.
AFTER Moissac things degenerated fast.
Besides, the system had degenerated.
The burlesque show has degenerated into decency.
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CEO of Professional Science Editing for Scientists @ prosciediting.com