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Structural deformities were observed on C. cornuta after treatment with 50 μg mL−1 of ZnO NPs.
Residual deformities were observed in 8 (16%) shoulders: varus deformity was seen in 4 shoulders (8%) and the deformity of the greater tuberosity in 4 (8%) (Table 3).
No gross physical deformities were observed in either the control or the high-fat group and litter size was not affected by the HFD.
Impaired growth and rickets-like skeletal deformities were observed in 33% of the children.
At the doses to 5 μM or 2.5 μM of SB-431542 or LY-294002, respectively, no deformities or very few deformities were observed.
Multiple vertebral deformities were observed in 6% of the entire cohort and 7% had one or more moderate or severe deformities.
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About 44% of the individuals observed showed at least one malformation and the highest occurrence of deformities was observed in the caudal region and in the vertebral column.
Hypodontia in patients without congenital deformities was observed twenty times rarer in boys and ten times rarer in girls.
Experimental studies on meat-type turkeys have shown that leg deformities are observed in birds characterized by decreased mechanical endurance and volumetric bone mineral density of tibia and femur [ 36].
No flexural limb deformity was observed in foals on either treatment.
No recurrence of the deformity was observed during the follow-up periods considered here.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com