Describe how each one has become stunted, blocked or deformed in their expression, in daily life.
Female mice lacking Wnt7a genes expression have deformed wall of the uterus and undeveloped ovaries [ 6].
The granules with reduced SBEIIa expression were deformed with irregular shape, looked deflated and were smaller than wild type.
Significant changes in gene expression that corelate with morphology are similar among normal to moderately deformed embryos, while severely deformed embryos show different patterns of gene expression.
Since the deformation map is conveniently prescribed in this work, it is possible to compare the performance of these deformation rules with the exact solution (i.e. the exact analytic expression for the deformed bond vectors) given directly by the deformation map.
By employing a no-tension material model with linear behaviour in compression, new analytical, closed-form expressions for deformed shape of the structure, location of the neutral axis in a generic cross section and axial displacement are provided.
While gene expression appears similar among embryos scored for no deformities (index 1), mild (index 2) and moderate (index 3), the most differences in gene expression patterns are among severely deformed (index 4) and extremely deformed (index 5) embryos.
Senescent hMSCs also exhibit changes in the shape of the nuclear lamina [ 4] and the nuclear lamina is deformed in cells with high p16INK4a expression.
Unexpectedly, patterns of gene expression among normal and moderately deformed embryos were similar, and only severely deformed embryos showed a contrasting pattern of gene expression.
