We note that gross examinations of morphometry of all healthy vs. smoke-exposed mice were insufficient for definitively determining the severity of disease.
The present study has some limitation; the number of patients studied was insufficient to definitively associate postsurgical hypoparathyroidism with increased fracture risk.
"The available evidence," Ratner concluded, "is insufficient to definitively determine if TZDs increase, reduce, or have a neutral effect on ischemic CVD or death".
The sample size was likely insufficient to definitively exclude an adverse effect of preoperative PTBD on OS after resection of PHC.
The experiment duration was insufficient to definitively evaluate t1/2 and AUC0 ∞; however, the interim parameters AUC0 last and Cmax, and Cmin and Tmax were all considered sufficient to meet the study objective and to confirm the published profile for anastrozole in post-menopausal women (Boeddinghaus and Dowsett, 2001; Plourde et al., 2004).
For some comparisons of specific mutations between our cases and the literature and also when we compare specific mutation with the rest, the number of events and cases is low and the statistical power is insufficient to definitively reject the null hypothesis (absence of difference in survival).
Clinical evidence is also insufficient to definitively establish a correlation between the age of RBCs being transfused and patient mortality; however, laboratory evidence has shown many storage-related changes that may result in impairment of blood flow and oxygen delivery at the microcirculatory level.
In the one patient with both intra- and extra-articular knee joint activity on PET/CT, SPECT/CT had insufficient resolution to definitively localise the Y-90 activity to the intra- or extra-articular space (Fig. 3).
Physical and sexual abuse in childhood/adolescence are risk factors for depression/anxiety in adulthood and the effect could be larger for women; however, currently there is insufficient evidence to definitively identify gender differences in the effects of maltreatment.
Despite these points, our review suggests that, at present, there is insufficient evidence to definitively confirm or refute this hypothesis in adult onset AIE.
