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The Multicenter InSync Randomized Clinical Evaluation (MIRACLE) is a large, prospective, randomized, double-blind, controlled trial designed to more definitively evaluate the clinical efficacy and safety of cardiac resynchronization for heart failure.
Thus, although IDPN may partially satisfy the nutritional needs of maintenance hemodialysis patients who have or are at risk of PEW and who have substantial, but not adequate, protein and/or energy intake, longer term randomized prospective clinical trials with appropriate control groups are necessary to more definitively evaluate the clinical effectiveness and indications for IDPN.
And they say that despite President Obama's pledge this year to be more transparent about the lethal operations, the U.S. is still releasing almost no information about who it is killing and why, making it impossible to definitively evaluate the legality of the strikes.
However, larger studies reflecting typical use would be necessary to definitively evaluate any treatment effect.
It would be feasible to definitively evaluate this intervention in a large multi-site trial.
We were not able to definitively evaluate pain on injection because the drug was infused through an ante cubital vein.
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An asylum seeker is someone whose refugee claim has not yet been definitively evaluated [ 3].
The influence of CYP2D6 genotype could not be definitively evaluated because of the small number of subjects from each CYP2D6 metabolizer class.
The efficacy of single-agent paclitaxel has not been definitively evaluated vs a standard salvage therapy in a randomised, phase III trial, however.
The final intervention programme, following modification and refinement in this feasibility study, is being definitively evaluated in an ongoing cluster-randomised controlled trial.
Common to all such studies, the sensitivity of the ELISPOT assay in diagnosis of M. tuberculosis infection in this population cannot be definitively evaluated in the absence of a gold standard.
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CEO of Professional Science Editing for Scientists @ prosciediting.com