This link should underpin future studies designed to definitively demonstrate causality.
"This suggests a spiral of silence might spill over from online contexts to in-person contexts, though our data cannot definitively demonstrate this causation," warns the report.
Further prospective and randomized clinical studies are necessary to definitively demonstrate whether BNP/NT‐proBNP‐guided therapy is able to significantly improve the outcome of patients with HF.
A second goal was to determine the sample size that would be necessary to definitively demonstrate efficacy of such a collaborative treatment program.
We definitively demonstrate that agonist immunotherapy can be effectively utilized to prevent this immunosuppressive effect, ultimately enhancing T-cell proliferation, effector T-cell cytotoxic activity, TH1 responses, and tumor-TIL homing.
In February, the National Academy of Sciences warned that the genetic analysis "did not definitively demonstrate" that the mailed anthrax was derived from spores grown in Dr. Ivins's laboratory.
Longer-term studies and positive controls will be needed to support these results to definitively demonstrate stimulation of chondrocyte differentiation, and particularly to verify that calcification without endochondral ossification does not occur as it does in shark cartilage.
These findings definitively demonstrate that 5-HT is secreted from the myocytes of the heart and strongly implied that 5-HT might play a certain role in cardiac physiology.
Although sharing the same conventional morphology and the same KRAS mutation does not definitively demonstrate relatedness, the primary and the recurrent lesions are likely related, due to the morphological similarities as well as sharing the less common G12R mutation in KRAS.
The review, by a panel convened by the National Academy of Sciences, says the genetic analysis "did not definitively demonstrate" that the mailed anthrax spores were grown from a sample taken from Dr. Ivins's laboratory at Fort Detrick in Frederick, Md. It does add, however, that the evidence is "consistent with and supports an association" between Dr. Ivins's flask and the attack anthrax.
Just as randomized controlled studies have failed to support primary prevention of dementia by using estrogen or nonsteroidal anti-inflammatory drugs (NSAIDs), there exists the possibility that well-designed randomized controlled trials might fail to definitively demonstrate putative or promising mild cognitive impairment interventions.
