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"Since complete data were not available, it is difficult to definitively assess the safety profile of fenofibrate plus simvastatin versus simvastatin plus placebo," the F.D.A. said in its staff report.
Given the large potential public health impact, additional, high quality epidemiologic studies are necessary to more definitively assess the risk.
These observations need to be confirmed in the future with studies that are of appropriate size and duration to definitively assess treatment benefit in these aspects of COPD.
A longer time series and detailed data on the state-level implementation (such as enforcement and testing resources) is required to definitively assess state effects.
To some extent, before we can definitively assess the impact of these policies, there may be a need for more time to allow for the policies to be translated into action.
Many observational, and a few interventional, studies in humans have supported these findings; however, there is a lack of well-designed prospective human interventional studies to definitively assess clinical outcomes.
Similar(10)
While the extent of the destruction has yet to be definitively assessed, part of the roof of the north transept, where the gift shop is located, has fallen in, and the potential for smoke and water damage is great.
The role of pretherapeutic imaging in SRT planning has not been definitively assessed.
Although both the tumor and thrombus turned into low density with slight marginal enhancement, the viability of the tumor cells could not be definitively assessed on the imaging diagnosis.
However, the role of lipid-lowering therapy in prevention of atherosclerotic events in SLE can be definitively assessed only in an intervention study.
5 The mechanism of action and the real contribution of metformin in reducing CV mortality was not definitively assessed in this study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com