Sentence examples for definitive sample size from inspiring English sources

Interim analysis after inclusion of 53 patients (50%) will provide the definitive sample size.

Assuming these values, the definitive sample size for the study was set at 604 subjects, randomised as described above.

Our pilot data support the idea that minimal or no adjustments to the definitive sample size calculation are required for losses to follow-up.

The FIRST pilot study recruited 50 patients in one year at two centres in Canada and Finland, providing feasibility data and allowing for greater precision for estimates of recruitment and the definitive sample size calculation.

Interim analysis after inclusion of 53 patients (50%) will provide the definitive sample size, which will be calculated based on the observed number of complications in the EBD group.

We planned a priori to transition directly from our pilot RCT to a definitive RCT if feasibility was established, with the pilot event rate used to inform the definitive sample size estimation.

Quantifying the current state of knowledge will help to inform dose selection decisions when evidence generation in the target population is deemed unethical or definitive sample sizes are not feasible, as may be the case, for example, when diseases are rare.

We estimated that 60 patients would represent approximately 5%to10%0% of the definitive RCT sample size (600 to 1200 patients), based on a pairwise comparison with an alpha of 0.05, a beta of 0.20 (80% power), a relative risk reduction of 50%, and a range of plausible SSI rates.

There are no definitive answers regarding sample size requirements for IRT, however sample sizes of 100 are often adequate [ 61].

Since this is a feasibility study which will indicate treatment effect for the design of a definitive study, the sample size is not determined by a power calculation.

Owing to low sample size, definitive conclusions cannot be drawn from the Betaseron Pregnancy Registry data.