Not definitive, just definite.
Predictive precision only approximates definitive knowledge but never equals it.
Timely molecular diagnosis, staging, and prognosis along with pharmacogenomic-based guidance can immediately engender a treatment shift from interim, phenotype-driven, population-based management to precision medicine with definitive, individualized therapies, and management plans, as well as drug exposures attuned to genotype and molecular prognosis [ 2].
An additional benefit is earlier tolerance of a soft/regular diet, but low precision and heterogeneity among studies preclude definitive conclusions.
Four months following surgery (April 2014), a definitive implant bar-retained maxillary obturator was fitted utilising precision attachments (Rhein attachments, Rhein83, NY, USA).
The FIRST pilot study recruited 50 patients in one year at two centres in Canada and Finland, providing feasibility data and allowing for greater precision for estimates of recruitment and the definitive sample size calculation.
The Supreme Court has consistently resisted providing more precision to materiality, despite efforts by companies seeking some definitive meaning to the term in certain contexts.
The data-set was of excellent quality, yielding low merging and refinement residuals, yet the precision of the Flack parameter is too low to enable a definitive statement to be made regarding the absolute structure (Flack & Bernardinelli, 2000 ▶).
Moreover, definitive characterization of the resulting intratumoural clonal heterogeneity is widely recognized to be a central requirement for precision medicine in haematology and oncology (2).
Applying a high-precision technique that dates rock deposits left behind by retreating glaciers, they compiled a definitive new history of the Cameron Glacier and improved histories of three other glaciers.
