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This study shows that there is a definitive limit in the ability of the PubChem3D sampled conformer models to reproduce the bioactive conformations found in PDB ligands.
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In many of these studies, sample sizes and multiple confounders in case definition limit definitive interpretation, leading some authors to conclude that socio-economic factors are mainly responsible for the variation in school performance and neurocognitive ability in asthma [ 32].
There is no definitive upper limit to the sophistication of the deceiving speaker's calculations (cf. Pagin 2011: Section 7).
When it comes to biological activity data analysis, the present study shows that there will be a definitive upper limit to the PubChem3D conformer ensemble accuracy based on the molecular size and flexibility.
Additionally, some preliminary results suggest that the upper reference limits for healthy newborns are higher than those for adults but definitive reference limits for newborns are not available.
Last August, judges in the New York Wine and Food Classic -- the definitive competition limited to the state's wines -- tasted Mythology blind, noticed a swirl of flavors, awarded it a gold medal and pronounced it the state's best red in 2001.
Mechanical stops provide definitive tactile limits, ensuring that the needle electrodes are deployed to the proper distance to achieve the ablation size as selected by the gynecologist.
Although identified structures may control the orientations of vent lineaments (Connor 1990; Magill et al. 2005), little is known about their influence on magma pathways for Harrat Rahat, so no definitive field-limiting factors can be assumed.
Cross-sectional data limit definitive conclusions about causation.
The retrospective aspect of our study and the small number of viral isolates limit definitive conclusions on the clinical manifestations of HPIV-4 infections.
Mr. Cameron said that while definitive information was limited, "there's growing evidence that we have seen, too, of the use of chemical weapons, probably by the regime".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com