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Exact(11)
Age at onset of definitive disease and survival duration were recorded.
Time to onset of definitive disease and survival time were also analyzed using the Kaplan-Meier and Cox proportional hazard methods (Figures 3, 4, Table 3).
Missed cases occur because only some participants receive biopsy, and definitive disease status ascertainment.
No definitive disease association has been established for these 5 astroviruses.
Only those patients with definitive disease defined by CT were considered to have sacroiliitis for all analyses.
Nevertheless, the key role played by Hnf-1b in the feedback loop of Figure 7 results in early and definitive disease onset in simulations when a haplodeficiency exists.
Similar(49)
There is general agreement that predictive genetic testing is indicated in asymptomatic relatives of a patient with HCM when a definitive disease-causing mutation has been previously characterized in the family.
For the nine traits currently measured under the BVA/KC scheme this would involve: 1) being clear on the extent to which traits are definitive of disease and which are biomarkers or secondary consequences, 2) analysing the genetic contribution to prediction of disease, and 3) deriving how the traits may be best weighted to provide the most accurate predictions.
Patients identified with definitive metastatic disease on CTS, or those unsuitable for radical treatment because of co-morbidities or frailty, are offered palliative treatments including best supportive care.
Furthermore, the mean age of patients with MC is similar to the perimenopausal age and to the first postmenopausal decade; therefore, low BMD in patients with chronic diarrhoea is not a specific indicator of definitive colonic disease.
A definitive proof for disease causality can be demonstration of disease-like phenotypes through genetic perturbation of the genes or alleles, which is obviously a daunting task for complex diseases where only mammalian models can be used.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com