Exact(2)
More cases of CAL (87.5%) were classified as definitive compared to HAL (80.0%) (p = 0.05).
Similarity values were ranked and genes whose cosine similarity was less than or equal to the median value of the distribution (cos ≤ 0.92) were considered significantly differentially expressed during the maturation of adult definitive compared to primitive erythroid cells.
Similar(57)
No significant difference in VEGF-A expression was found between baseline and day 14, but a significant reduction at the definitive surgery compared with baseline was observed (P=0.007).
Although numbers were too small for definitive assessment, compared with Determine™, this provided a sensitivity of 50% and specificity of 100% for 'Advanced Quality™ Rapid Anti-HIV 1&2', in contrast with the information provided in the package insert [ 17].
We observed a marked suppression of the Ki67 proliferation index after 14 days in the 11 patients that could be evaluated (P<0.00001), and there was a significant reduction in Ki67 index at definitive surgery compared with baseline (P=0.03).
There was a significant reduction in COX-2 expression in the EXE COXIB arm (P<0.03) at definitive surgery compared with the initial biopsy, but no significant difference was observed between biopsies in the EXE arm.
Sensitivity analyses were performed to investigate whether consistent results were found among patients with a definitive diagnosis compared to those with a presumptive or possible diagnosis and also to determine the relationship between type of TB diagnosis and death in the first 12 months of follow-up, where mortality is known to be the worst, particularly in Eastern Europe [ 13].
In a larger study of premenopausal women treated with cyclofosfamide, metotrexate and 5-fluorouracil (CMF) a DFS advantage was demonstrated only for a smaller group of patients (oestrogen receptor absent tumours) treated within 3 weeks after definitive surgery compared with the patients treated later (Colleoni et al, 2000).
A definitive trial, comparing current standard management with novel strategies not primarily intended to achieve ductal closure, may be necessary to resolve doubts regarding the quality or conduct of prior studies.
This embarrassment of riches, however, besieges men with a bewildering array of treatment choices, conflicting advice from doctors and a lack of definitive studies comparing the options.
A definitive study comparing the fracture effectiveness of raloxifene and alendronate has not been published [ 11].
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