While no definitive activity was observed in either study, these investigations are still at the early stages.
Prucalopride in a dose of 1 or 2 mg appeared also to have definitive activity in patients with constipation due to spinal cord injury.
A large number of agents have been evaluated for the treatment of advanced STS over the last 30 years, but only a handful have shown definitive activity (Spira and Ettinger, 2002).
After all, IPOA's exhortative but toothless Code of Conduct, Article 3.3, states "Signatories shall take firm and definitive action if their personnel engage in unlawful activities.
Micro-local hotspots of parasite transmission to intermediate hosts in a landscape, as well as areas of higher risk for human contamination in village and urban settings, may be explained by the definitive hosts' activity patterns and defecation behaviour.
However, because solutions of soluble Aβ oligomers in the neurobasal medium used in this study have been shown to change with time [ 19], it is not possible to draw definitive structure-activity conclusions from the results of this study.
During the definitive care phase, activities concentrate in and around the ICU.
The occurrence of tropical cyclones in the Mediterranean Sea is generally extremely rare, with an average of 1.57 forming annually and merely 99 recorded occurrences of tropical-like storms discovered between 1948 and 2011 in a modern study, with no definitive trend in activity in that period.
However, the definitive diagnosis of activity within a specific tissue requires a tissue biopsy.
19 In conclusion, bortezomib monotherapy demonstrated definitive signs of activity in patients with heavily-treated relapsed and refractory ATL; however, its overall efficacy was not sufficiently promising.
