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Moreover, MADRS based definitions of remission vary.
Definitions of remission that are better associated with longer-term outcomes are needed.
As shown in Fig. 3a, patients with anxiety at baseline were statistically significantly less likely to achieve remission than those without anxiety at baseline, according to both definitions of remission (YMRS Total score of <12 and <8 at Day 21).
Validity of alternative definitions of remission requires a separate study.
Definitions of remission and response have been described previously [ 7].
Finally, we could not examine the influence of different definitions of remission.
Sixth, our results are partially dependent on methodological decisions about operationalizing definitions of remission.
Predictive validity was a critical element in the selection of definitions of remission for RA.
Our definitions of remission were based on the 2009 ADA consensus statement (10).
The ACR/EULAR definitions of remission were developed using data from trials.
In addition, the two studies use different operational definitions of remission.
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