Sentence examples for definition of breakthrough from inspiring English sources

Constructal can thus define effective guidelines for the future development of transport vehicles allowing also the definition of breakthrough configurations, which can produce major advantages if compared to the technological maturity scenario, in which today transport industry is operating.

Defining an algorithm for the timing and indications for treatment switch would be of great clinical utility but requires a consensus definition of breakthrough disease.

In all groups, the definition of breakthrough disease and the decision to recommend a switch was made by each patient's UCSF MS Center neurologist.

A standard definition of breakthrough disease should be established in order to promptly identify sub-optimal responders to first-line therapies who may benefit from switching to second-line therapies.

A further potential problem is that the threshold for recommending a switch may differ among our center's neurologists, in part due to the lack of definition of breakthrough disease.

Although there is currently no unanimous definition of breakthrough pain in chronic malignant or non-malignant pain, a consensus panel recommendation from 2005 suggested that breakthrough pain should be defined as 'an abrupt, short-lived, and intense pain that "breaks through" the around-the-clock (ATC) analgesia that controls persistent pain'.

The creation and worldwide spread of the Internet, and then smartphones, are the very definition of "miraculous breakthroughs that altered lives".

The double design process allows overcoming any limitation about the configurations and allowing the definition of the necessary breakthrough innovations, which could revitalize the market in sectors, which appears mostly limited to the substitution.

We find that the success of breakthrough predictions is highly sensitive to the definition of the rock-physics transform; it is therefore important to model this transfer function accurately.

Another breakthrough is the definition of the differential roles of IFN-λs in contrast to type I IFNs in IAV infection using Ifnlr1−/−, Ifnαr1−/− and Ifnlr1−/− Ifnαr1−/− mice (Galani et al., 2017).

The breakthrough relies on the definition of a suitable footbridge between the two methods, through the design of compatibility condition.