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This syndrome awaits definite validation, but several cases have already been reported [1 3].
After the comprehensive and definite validation, future use of the biomarkers would complement CT in lung cancer screening for the early detection of lung cancer.
However, these ranked rules must be reviewed by a human (physician) for definite validation, in the absence of any existing reference for multi-elements rules.
Although definite validation of the value of this approach will require prospective studies in larger patient groups, our scoring system seems useful, as it allows preoperative identification of young patients with suspected ovarian malignancy, in which a borderline ovarian tumor is the most likely diagnosis.
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4 Validation of these predictions by a randomised controlled trial of the effects of long term reduction in dietary salt on morbidity and mortality from cardiovascular disease would provide definite proof.
What will validation validate?
For the validation study, definite self-harm was the outcome of interest so we used all the Read codes that we included in this category.
Not definitive, just definite.
Not every validation test yields definite result.
Other variants merit further validation to establish their definite role in explanation of interindividual differences in the outcome of capecitabine-based therapy.
This could be done if all efforts in this field are integrated together to obtain a clear and definite steps for prognostics system design, development, validation, and verification.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com