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"There are very definite side effects.
With the combination of the anticonvulsant topiramate and phentermine (the latter approved in 1959) in doses one-quarter to one-half of those typically used with both agents, weight loss again was seen, with acceptable although definite side effects, including paresthesia in 16 23% vs. 3% of those on placebo and dry mouth in 13 and 19% versus none on placebo.
Similar(58)
Furthermore, despite great alterations in the parameters assessed thought to reflect MAO activity and NO synthesis, no definite psychiatric side effects were encountered rendering it unlikely that these factors are involved in IFN-α-induced mood alterations.
However, in an older man without prostate cancer, there is at least a small amount of evidence that testosterone will increase bone density, but there is definite concern about potential side effects.
However, after all this result is not so surprising, since no definite clinically relevant IFN-α induced psychiatric side effects were observed in this patient cohort (Bannink et al. 2008).
Hence, research has been focused on search for new anti-ulcer molecules from medicinal plants as these molecules are more relevant to living system and already have definite biological functions and thus, may have fewer side effects.
Although the response rate was low, gefitinib offers definite palliation in pretreated advanced NSCLC, with few side effects.
There were side effects.
Xiaflex has side effects, though.
There are also side effects.
Any other damaging side effects?
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