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The definite mechanisms of HIF-2 activity during digestive system cancers remain elusive.
Second, although data have been amassed delineating the mechanisms and consequences of increased HIF-2 activity during cancer progression, its definite mechanisms remain elusive in digestive system cancers.
Although definite mechanisms have yet to be established, IP6 activity has been reported to involve several processes (Fox and Eberl, 2002).
Furthermore, various cytokines (e.g., IL-15 and IL-17) are involved in signaling pathways in which ULBP1 takes part, although definite mechanisms and signals regulating their activation remain to be elucidated.
The relation between PA and prostate cancer risk was classified as 'probable' with respect to decreased risk, by the IARC in 2002, 42 but no definite mechanisms have been identified for a relation between PA and prostate cancer.
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He explained in 1946 that Turing's 'great positive contribution' was to show that 'one, definite mechanism can be "universal"'; and in a 1949 lecture he emphasized the crucial importance of Turing's research, which lay, he said, in Turing's 1936 demonstration that a single appropriately designed machine 'can, when given suitable instructions, do anything that can be done by automata at all'.
The definite mechanism that confers NMD-resistance still remains unanswered although it has been suggested that spatial rearrangements of the 3'UTR that affect the distance between PTC and poly(A) tail can modulate the NMD pathway [36].
Hence, the definite mechanism remains unknown.
However, they did not unravel the definite mechanism between them until now.
Thus IGFBP5 is an important player of CC cell growth, but definite mechanism is unknown.
The definite mechanism responsible for decreasing serum selenium level after H. pylori eradication therapy is not clearly defined.
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